Table 9 Sensitivity, specificity, PPV, and NPV for probability cut-off points
Method 1 | Method 2 | |
|---|---|---|
Cut-point 1 (MLE) | Probability .45 | Probability .41 |
Sensitivity | 52.1 % | 18.3 % |
Specificity | 74.0 % | 96.2 % |
PPV | 61.8 % | 55.3 % |
NPV | 65.7% | 81.9 % |
Cut-point 2 (Sen. 90%) | Probability .33 | Probability .13 |
Sensitivity | 90.9 % | 89.8 % |
Specificity | 17.6 % | 28.0 % |
PPV | 47.1 % | 20.6 % |
NPV | 70.5 % | 91.3 % |
Cut-point 3 (Sen. 80%) | Probability .37 | Probability .15 |
Sensitivity | 80.5 % | 78.2 % |
Specificity | 37.1 % | 45.0 % |
PPV | 50.9 % | 28.7 % |
NPV | 70.2 % | 88.8 % |
Cut-point 4 (Spc. 80%) | Probability .48 | Probability .23 |
Sensitivity | 39.9 % | 45.8 % |
Specificity | 81.4 % | 79.5 % |
PPV | 63.4 % | 36.7 % |
NPV | 62.6 % | 85.0 % |