Fig. 2
![Fig. 2](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12894-024-01472-1/MediaObjects/12894_2024_1472_Fig2_HTML.png)
DEGs identification in LNCaP and PC3 cells after erastin exposure. (a) Principal component analysis (PCA) of RNA-seq data. (b) The correlation analysis results were consistent with PCA. (c) Volcano plot analysis identifies the DEGs of erastin-induced LNCaP groups; red and green dots represent 447 and 495 upregulated and downregulated genes, respectively. (d) Heatmap of LNCaP groups after erastin exposure. (e) Volcano plot analysis identifies the DEGs of PC3 groups; red and green dots represent 3,704 and 1,921 upregulated and downregulated genes, respectively. (f) Heatmap for PC3 groups after erastin exposure. (g) Venn diagram of erastin-induced DEGs