Table 1 Identification of bidirectional causal relationship between insomnia and BPH by six distinct MR methods
Exposure | Outcome | MR method | OR (95% CI) | P-value |
|---|---|---|---|---|
Insomnia | Hyperplasia of prostate | IVW | 1.267 (1.003, 1.601) | 0.048 |
MR Egger | 1.296 (0.678, 2.478) | 0.451 | ||
Weighted median | 1.283 (0.995, 1.655) | 0.055 | ||
Maximum likelihood | 1.281 (1.073, 1.530) | 0.006 | ||
Weighted mode | 1.257 (0.890, 1.777) | 0.221 | ||
Hyperplasia of prostate | Insomnia | IVW | 1.026 (1.000, 1.052) | 0.048 |
MR Egger | 1.015 (0.930, 1.109) | 0.739 | ||
Weighted median | 1.023 (0.987, 1.061) | 0.213 | ||
Maximum likelihood | 1.027 (1.001, 1.053) | 0.046 | ||
Weighted mode | 1.028 (0.961, 1.099) | 0.424 |